Product Details
Product name:organic citric acid CAS NO 501-30-4 EINECS NO 207-922-4INCI Name Kojic Acid Chemical name 5-Hydroxy-2-(Hydroxymethyl)-4H-Pyran-4-OneMolecular weight C6H6O4 molecular formula 142.11 SolubilitySoluble in water, alcohol, acetone|, slightly soluble, ether, ethyl acetate, chloroform and pyridine, insoluble in a benzeneSafety This non-toxic, non-stimulation, no side effectsQuality indicators Appearance white crystals or powder melting point 152~155°CContent ≥99.0%Dry weight loss less than 0.5%Burning residu less than O.1%Iron less than 10ppmArsenic less than1ppm Chlorides less than 50ppm Heavy Metal (asPb )(%) less than 0.001aflatoxin NoneMicrobiological Experiment bacilus ≤3000CFU/gcolibacillus femininefungi ≤50CFU/g toxicity test LD50 2500-3500mg/kgCPU Mechanism of Action Kojic acid by inhibiting cell activity, reducing the activity of tyrosinase, to prevent oxidation of DOPA freckle whitening effect. Non-cells in vitro tests, can effectively inhibit the activity of tyrosinase, non-competitive manner inhibited. It will and copper ions, thereby losing the copper ion activation of tyrosinase.and copper ions that copper ion lost on tyrosinase activity role thus blocking or slowing down the formation of melaninApplication 1,Apply to cosmetics field.cosmetics and other senior freckle,In the human body skin, the tyrosine under the cream ammonia enzyme's catalytic effect, with the oxygen free radical after the complex oxidation, the polymerization, then synthesizes the melanin , Kojic acid can inhibit the tyrosinase synthesis, so it’s very strong to inhibit skin melanin formation so that Kojic acid has been mixed in cosmetics, facial mask, cream, skin cream, made whiten cosmetic that is effectivee in the treatment of freckles, age spots, pigmentation, acne and so on . 20ug/ml concentration of Kojic acid can inhibit a variety of tyrosinase (or PPO PPO) 70 ~ 80% of energy. 2,In food process field, Kojifc Acid use for food additive, function as the anticorrosion, to maintain freshness, anti- oxidation.Laboratory shows Kojic Acid can inhibit the sodium nitrite transforms as the carcinogenic nitrosamine in bacon,and add some kojic acid in foods, it’s not effective the tasteless, fragrance, and texture, Meanwhile kojic acid is a material that make malt phenol and ethyl malt phenol ,During the food processing ,kojic acid is widely used in many fields. 3,In the field of medicine,Since kojic acid is not mutation to eukaryotic cell ,and can eliminate free radicals in human body, increased white blood cell motility functions, it’s useful to healthy, so kojic acid as the material of cephems antibiotic, produce the finish products Used in the treatment of diseases such as headache, toothache ,it’s very satisfactory use in analgesic ,anti-inflammatory effects. 4,In the agricultural field,Kojic acid can apply in the production of bio-pesticides.Add 0.5 ~ 1.0% Kojic acid made from bio-fertilizer (dark red liquid), whether they are of low concentration as foliar fertilizer for spraying or system to root growth and increasing agent, this crop production enhancers on grain and vegetables have a significant effect. 5,In other areas, Kojic acid can also be used as iron analysis reagents, such as film despeckle . Packing and storage 1,aluminum foil bags 1kg/bag2,barrel 25kg/barrel.(inside plastic bag. Aluminum foil bag,barrel . outside plastic protective film) or according to clients' requirementConfined, a cool, dark preservation, shelf-life of two years.